Natural Immune & Seasonal Wellness Support with Apogen®
What Is Apogen®?
Apogen® is a nutritional ingredient derived from a proprietary Spirulina (FEM-101) microalgae extract. It contains a complex profile of naturally occurring bioactive components, including allophycocyanin (APC), C-phycocyanin (CPC), spirulina growth factors, sulfated polysaccharides, peptides, nucleic acids, amino acids, and trace elements.
Apogen® is designed for use as a dietary and functional food ingredient, supporting overall wellness as part of a balanced nutritional approach.
Apogen®: Functional Microalgae Protein Ingredient
Apogen® is a functional food ingredient and nutritional protein extract derived from a proprietary strain of Spirulina platensis (FEM-101). The following overview details its properties and the scientific research exploring its role in supporting human health.
1. Nutritional Composition and Mechanism of Action
Apogen® is characterized by a high concentration of bioactive phycobiliproteins, including Phycocyanin, Allophycocyanin (APC), and sulfated polysaccharides.Rather than acting as a traditional medicine, Apogen® is positioned as seasonal support, designed to maintain the body's natural defense mechanisms. Its primary physiological functions involve:
- Physical Constitution Adjustment: Supporting the body’s ability to adapt to environmental challenges and seasonal variations.
- Physiological Barrier Support: Contributing to the maintenance of the body's natural external barriers and internal immune-modulation pathways.
- Cellular Defense Support: Providing essential nutrients, such as nucleotides and trace elements, that serve as building blocks for physiological maintenance.
2. Scientific Research and Study Types
The bioactive potential of Apogen® has been explored through various experimental frameworks. These studies do not imply definitive human clinical outcomes but offer insights into the ingredient's potential mechanisms.
● Cellular/Experimental Research (In Vitro):
◦ Experimental data indicates that the extract shows inhibitory potential against the formation of viral plaques in laboratory settings (including models for Influenza A/B, RSV, and SARS-CoV-2).
◦ Research indicates a reduction in the expression of specific markers related to tissue stress in lung cell lines.
● Preclinical Animal Research (In Vivo):
◦ In mouse models, administration of the extract was associated with improved survival rates and a reduction in markers of viral replication during experimental influenza and enterovirus challenges.
◦ Animal models exploring auditory health indicated that the extract may support the maintenance of the Auditory Brainstem Response (ABR) threshold and protect against markers of oxidative damage in the cochlea.
● Clinical Observational Data:
◦ A prospective, randomized, open-label, parallel-controlled clinical trial was conducted to observe the use of Apogen® lozenges as an adjuvant nutritional support for individuals with mild to moderate COVID-19 symptoms. The study observed a trend toward faster recovery of normal body temperature and a reduction in reported fatigue markers compared to the control group.
3. Safety and Quality Standards
Apogen® is manufactured under strict quality systems, including ISO 22000:2018 and HACCP.
- Preclinical Safety Profile: Toxicological studies in Sprague-Dawley rats demonstrated that the extract is well-tolerated at oral doses as high as 5,000 mg/kg (acute) and 3,000 mg/kg/day for 14 successive days (subacute).
- Ingredient Purity: It is a Non-GMO, Vegan, and Gluten-free (less than 20 ppm) nutrient source.
4. Usage Considerations
The recommended dosage is 50-60mg/day for kids below 12 years old and 100-120mg/day for over 12 years old, making the finished product cost in line with market standard. It is possible to increase daily dosage to the efficacy level in the market segment that you want to develop: joint care, inner ear support, It contains slight algae taste and natural blue color. It is advised not to expose to directly light exposure.To preserve the bioactivity of the natural proteins, Apogen® should be consumed with cool or lukewarm food or liquids below 50°C (122°F). It is available in various delivery formats, including liquid drops, nutrient powders, and chewable tablets, to suit different dietary preferences.
5. Application (Dietary Supplement Applications)
Apogen® is water-soluble and suitable for a variety of supplement formats, including:
- Capsules and tablets
- Powders and granules
- Chewable tablets and lozenges
- Liquid formulations
Food & Beverage Applications
As a functional nutritional ingredient, Apogen® may be incorporated into:
- Yogurt and dairy products
- Juice and beverage formulations
- Milk, ice cream, and confectionery products
- Chewing gum and jelly products
Apogen® is suitable for daily use within food and nutrition formulations, subject to applicable local regulations.
Patents Protections.
1.Patent claims include pharmaceutical compositions and manufacturing processes of Apogen
2.Regions: US, EU, China, Japan, South Korea, India, Australia, Taiwan, and many other regions
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Apogen® Medical Publication
Scientific Studies
Our research paper published in the Journal of Medical Virology 70:119–125 (2003) based on Apogen's abilities to inhibit viruses. We have also conducted...
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