Far East Bio-Tec Co., Ltd. - FEBICO -Organic Chlorella, Organic Spirulina and Dietary Supplements Manufacturer in Taiwan .

Apox ® Spirulina extract for Apox ® Spirulina extract | 100% Made in Taiwan Organic Spirulina & Chlorella Manufacturer | Far East Bio-Tec Co., Ltd.

Apox ® Spirulina extract manufacturer. ApoX® is a natural Spirulina-derived extract rich in specific sulfated polysaccharides that exert potent heparanase inhibitory and viral neutralization activity. FEBICO is a Taiwan manufacturer of Organic Chlorella, Organic Spirulina and Dietary Supplements for Apox ® Spirulina extract since 1976. FEBICO (Far East Bio-Tec. Co. Ltd.) is an ISO-22000 and HACCP certified Taiwan manufacturer with more than 4-decades of experiences in producing microalgae based raw materials and finished products, including Chlorella, Spirulina, Chlorella Growth Factor CGF, patented microalgae extract, Nattokinase, probiotics and nutritional supplements. Apart from seeking distributors of FEBICO brand products, we're offering raw materials, finished products, private labeling and OEM/ODM services.

Spirulina extract | 100% Made in Taiwan Organic Spirulina & Chlorella Manufacturer | Far East Bio-Tec Co., Ltd.

Spirulina extract / With nearly 50 years of experience, FEBICO is committed to providing high-quality microalgae superfoods and health supplements to our global customers, along with exceptional service.

Spirulina extract

Apox ® Spirulina extract

ApoX® is a natural Spirulina-derived extract rich in specific sulfated polysaccharides that exert potent heparanase inhibitory and viral neutralization activity.

How ApoX works?
1.Viral Entry Inhibition: When dissolved or formulated in aqueous platforms, ApoX® creates a breathable physical and biochemical protective barrier over dermal and epithelial surfaces. It blocks viral envelope glycoproteins from adhering to cell surface receptors (such as heparan sulfate proteoglycans).
2.Cellular & Dermal Integrity: By inhibiting viral adhesion and cellular heparanase activity, ApoX® prevents cell entry, reduces downstream inflammatory cascades, and maintains structural skin/epithelial integrity.
3.High Safety Profile: Derived from food-grade microalgae with a long history of safe use. Comprehensive animal toxicology, skin sensitivity, and dermal irritation studies confirm that high-dose ApoX® exposure causes zero skin sensitization, ocular toxicity, or localized irritation.

Target Applications & Strategic Partnership Opportunities

FEBICO is actively seeking global CDMO, pharmaceutical, cosmetic, and medical device partners to commercialize ApoX® across high-growth healthcare sectors

1. Environmental Surface Disinfectants & Sanitizers

Market Position: Ready-to-market formulation for alcohol-free surface and personal sprays.

Value Prop: Non-corrosive, non-irritating, providing continuous 24-hour surface antiviral defense.

2. Cosmeceuticals & Personal Care (Gels, Creams, Serums)

Market Opportunity: Ideal for barrier repair, sensitive skin care, post-procedure recovery, and anti-pollution formulations.

Regulatory Status: INCI listing application for Spirulina Extract is currently underway (Target completion: Q4 2026). Upon INCI registration, ApoX® can be seamlessly integrated into global cosmetic SKUs as an active ingredient promoting skin defense and cellular integrity.

3. Medical Devices (Nasal Sprays, Throat Sprays, Oral Rinses)

Market Opportunity: Prevention and adjunctive care for upper respiratory viral infections (e.g., benchmarked against leading barrier sprays like Viralize).

Collaboration Model: Seeking Class I / Class II Medical Device manufacturers and distributors for co-development, OEM/ODM manufacturing, and regulatory filing for nasal/oral protective sprays.

4. Biopharmaceuticals & Prescription Topicals (OTC/Rx)

Market Opportunity: Topical therapeutics for recurrent viral skin lesions (e.g., HSV-1 cold sores, HSV-2 genital herpes, Hand-Foot-and-Mouth disease lesions).

Collaboration Model: Open for Out-Licensing, Joint R&D, and Clinical Co-development with pharmaceutical partners seeking novel, non-resistant natural antiviral compounds.

Mechanism of actions
ApoX is a potent, cell-permeable, and orally active heparanse inhibitor.
Global Intellectual Property (IP) Portfolio
ApoX® is backed by robust international patents covering "Cyanobacterial extracts, processes for preparing the same, and uses thereof" in US, EU, JP, KR, TW, MY, SG

Scientific studies

ApoX® exhibits outstanding antiviral potency coupled with remarkably low cytotoxicity. A Selectivity Index (SI) > 10 indicates strong potential for therapeutic translation, while an SI > 50 signifies exceptional potency with minimal host toxicity. ApoX® achieves SI values exceeding 10,000 on key dermatological and mucosal viral pathogens (e.g., CVA16, HSV-2, EV71), providing an exceptionally wide safety margin for topical, mucosal, and therapeutic applications.

ApoX® exhibits outstanding antiviral potency coupled with remarkably low cytotoxicity. A Selectivity Index (SI) > 10 indicates strong potential for therapeutic translation, while an SI > 50 signifies exceptional potency with minimal host toxicity. ApoX® achieves SI values exceeding 10,000 on key dermatological and mucosal viral pathogens (e.g., CVA16, HSV-2, EV71), providing an exceptionally wide safety margin for topical, mucosal, and therapeutic applications.
Global Intellectual Property (IP) Portfolio

ApoX® is backed by robust international patents covering the following region: US/EU/JP/KR/TW/MY/SG. Cyanobacterial extracts, processes for preparing the same, and uses thereof" in the following region.

United States: US 11,246,898 B2/European Union: EP 3676367/Japan: JP 7544801/South Korea: KR 10-2353119/Taiwan: TW I763916/Malaysia: MY-203205-A/Singapore: SG 11202001154Q

How ApoX works?

1.Viral Entry Inhibition: When dissolved or formulated in aqueous platforms, ApoX® creates a breathable physical and biochemical protective barrier over dermal and epithelial surfaces. It blocks viral envelope glycoproteins from adhering to cell surface receptors (such as heparan sulfate proteoglycans).

2.Cellular & Dermal Integrity: By inhibiting viral adhesion and cellular heparanase activity, ApoX® prevents cell entry, reduces downstream inflammatory cascades, and maintains structural skin/epithelial integrity.

3.High Safety Profile: Derived from food-grade microalgae with a long history of safe use. Comprehensive animal toxicology, skin sensitivity, and dermal irritation studies confirm that high-dose ApoX® exposure causes zero skin sensitization, ocular toxicity, or localized irritation.

Dosage forms and specifications
  • Form: powder
  • Color: beige to yellowish brown
  • Transportation temp: Room temperature
  • Shelf life: 2 years
  • Bioassay: Anti-Enterovirus 71 virus
Product Features

1. Non-Toxic & Safe: 100% Alcohol-free, non-sensitizing, and non-irritating to skin and mucous membranes.
2. Extended Protection: Sustained broad-spectrum antiviral activity for up to 24 hours.
3. Patented Natural Antiviral Shield: Proprietary, highly-standardized Spirulina extract rich in bioactive sulfated polysaccharides.
4. Multi-Market Versatility: Ideal for OTC topical formulations, medical devices, active cosmetic ingredients, and surface disinfectants.

Source References

Apox is Recognized in the Epidemic Prevention Category by the Institute for Biotechnology and Medicine Industry (IBMI) in Taiwan for validated efficacy, safety standards, and manufacturing excellence in viral barrier sprays. https://www.snq.org.tw/chinese/02_products/02_detail.php?pdid=3927


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Apox ® Spirulina extract for Apox ® Spirulina extract | 100% Made in Taiwan Organic Spirulina & Chlorella Manufacturer | Far East Bio-Tec Co., Ltd.

Located in Taiwan since 1976, Far East Bio-Tec Co., Ltd. has been a chlorella, spirulina and dietary supplements manufacturer. Their main products, include , Organic Spirulina, Organic Chlorella, Spirulina Natural, Chlorella Natural and Nutritional Supplements, which are produced with advanced fermentation facilities to produce high-quality nattokinase and spore-forming probiotics.

With nearly 50 years of experience, FEBICO is committed to providing high-quality microalgae superfoods and health supplements to our global customers, along with exceptional service. Manufacturer of spirulina and chlorella (organic certified and natural) in Febico brand finish product, raw powder, bulk tablets, private labeling and OEM/ODM.

FEBICO has been offering customers Naturland / EU and USDA-NOP certified chlorella, spirulina and dietary supplements, both with advanced technology and 47 years of experience, FEBICO ensures each customer's demands are met.